The Universe of Microbiome and how it Influences our Health Outcomes
DOI:
https://doi.org/10.26438/ijsrbs.v12i1.668Keywords:
Microbiome, Human health, Immune functions, Gastrointestinal tract, Respiratory tract, Nasal cavity, skin surfaceAbstract
The human microbiome consists of bacteria, archaea, viruses, and eukaryotes that inhabit both our internal and external environments. These microorganisms influence human physiology, affecting our health status, and can enhance or impair our metabolic and immune functions. Microbes can be found in many different places in the human body and have adapted to each location. For example, certain types of microbes are more common in the gastrointestinal tract, while others inhabit the respiratory tract, nasal cavity, and skin surface. The microbes that naturally live in the human body have become well-suited to interacting with the immune system over time. Changes in the microbial community in the intestines play a significant role in human health and the development of diseases. These changes can be due to lifestyle or the presence of an underlying disease. Imbalance in the microbiota can make the body more susceptible to infections, with the likelihood of infection depending on which part of the body is affected. The various kinds of microbes found in the human body have different metabolic activities and functions depending on their location. It is crucial to understand the composition and activities of the human microbiome in order to understand the impact on human health and disease.
References
Singh, Rasnik K et al. “Influence of diet on the gut microbiome and implications for human health.” Journal of translational medicine Vol.15,1 73, 2017
Malla, Muneer Ahmad et al. “Exploring the Human Microbiome: The Potential Future Role of Next-Generation Sequencing in Disease Diagnosis and Treatment.” Frontiers in immunology Vol.9 pp.28-68. 2019.
Chaudhary, Prem Prashant et al. “Does "all disease begin in the gut"? The gut-organ cross talk in the microbiome.” Applied microbiology and biotechnology, Vol.108, 339, 2024.
Hamjane, Nadia et al. “Gut microbiota dysbiosis -associated obesity and its involvement in cardiovascular diseases and type 2 diabetes. A systematic review.” Microvascular research Vol.151,104601, 2024
Yang, Ge et al. “Role of the gut microbiota in type 2 diabetes and related diseases.” Metabolism: clinical and experimental Vol.117,154712, 2021.
Li, Yujiao et al. “Dysbiosis of Oral Microbiota and Metabolite Profiles Associated with Type 2 Diabetes Mellitus.” Microbiology spectrum, Vol.11, 2023
Tang, Sha-Sha et al. “Intermittent hypoxia is involved in gut microbial dysbiosis in type 2 diabetes mellitus and obstructive sleep apnea-hypopnea syndrome.” World journal of gastroenterology Vol.28, Issue.21, pp.2320-2333, 2022
Kulkarni, Prasanna et al. “Could dysbiosis of inflammatory and anti-inflammatory gut bacteria have an implication in the development of type 2 diabetes? A pilot investigation.” BMC research notes Vol.14,52, 2021.
Ojo, Omorogieva et al. “The Role of Dietary Fibre in Modulating Gut Microbiota Dysbiosis in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.” Nutrients, Vol.12, Issue.11, pp.32-39. 2020
Sikalidis, Angelos K, and Adeline Maykish. “The Gut Microbiome and Type 2 Diabetes Mellitus: Discussing a Complex Relationship.” Biomedicines, Vol.8, 2020,
Ortega, Miguel A et al. “Type 2 Diabetes Mellitus Associated with Obesity (Diabesity). The Central Role of Gut Microbiota and Its Translational Applications.” Nutrients Vol.12, pp.27-49, 2020,
Sharon, Itai et al. “The Core Human Microbiome: Does It Exist and How Can We Find It? A Critical Review of the Concept.” Nutrients Vol.14, pp.28-72, 2022
Manos, Jim. “The human microbiome in disease and pathology.” APMIS : acta pathologica, microbiologica, et immunologica Scandinavica Vol.130, Issue.12, pp.690-705, 2022
Sepich-Poore, Gregory D et al. “The microbiome and human cancer.” Science (New York, N.Y.) vol.371, 6536. 2021
Hoshino, Tatsuhiko et al. “Global diversity of microbial communities in marine sediment.” Proceedings of the National Academy of Sciences of the United States of America vol.117,44: pp.27587-27597. 2020
Rubin, Benjamin E et al. “Species- and site-specific genome editing in complex bacterial communities.” Nature microbiology vol.7,1: pp.34-47. 2022
Dueholm, Morten Kam Dahl et al. “MiDAS 4: A global catalogue of full-length 16S rRNA gene sequences and taxonomy for studies of bacterial communities in wastewater treatment plants.” Nature communications Vol.13,1 1908. 2022
Gomaa, Eman Zakaria. “Human gut microbiota/microbiome in health and diseases: a review.” Antonie van Leeuwenhoek, Vol.113,Issue.12, pp.2019-2040. 2020
Fousekis, Fotios S et al. “Inflammatory Bowel Disease and Patients with Mental Disorders: What Do We Know?” Journal of clinical medicine research Vol.13,9: pp.466-473. 2021
El-Hakim, Yumna et al. “Impact of intestinal disorders on central and peripheral nervous system diseases.” Neurobiology of disease Vol.165: 105627, 2022
Konstantinidis, Theocharis et al. “Effects of Antibiotics upon the Gut Microbiome: A Review of the Literature.” Biomedicines, Vol.8,502, 2020.
Fishbein, Skye R S et al. “Antibiotic perturbations to the gut microbiome.” Nature reviews. Microbiology Vol.21, Issue.12, pp.772-788, 2023.
Bolte, Laura A et al. “Long-term dietary patterns are associated with pro-inflammatory and anti-inflammatory features of the gut microbiome.” Gut Vol.70, Issue.7, pp.1287-1298, 2021.
Beam, Ashley et al. “Effect of Diet and Dietary Components on the Composition of the Gut Microbiota.” Nutrients, Vol.13, pp.27-95, 2021.
Dahl, Wendy J et al. “Diet, nutrients and the microbiome.” Progress in molecular biology and translational science Vol.171, pp.237-263, 2020.
Sidhu, Shaneerra Raajlynn Kaur et al. “Effect of Plant-Based Diets on Gut Microbiota: A Systematic Review of Interventional Studies.” Nutrients Vol.15, 1510, 2023.
Miao, Zelei et al. “Gut microbiota signatures of long-term and short-term plant-based dietary pattern and cardiometabolic health: a prospective cohort study.” BMC medicine vol.20,1 204. 2022.
Toribio-Mateas, Miguel A et al. “Impact of Plant-Based Meat Alternatives on the Gut Microbiota of Consumers: A Real-World Study.” Foods (Basel, Switzerland) vol. 10,9 2040. 2021.
Mancin, Laura et al. “Effect of 30 days of ketogenic Mediterranean diet with phytoextracts on athletes' gut microbiome composition.” Frontiers in nutrition vol. 9 979651. 2022.
Deledda, Andrea et al. “Dynamics of Gut Microbiota and Clinical Variables after Ketogenic and Mediterranean Diets in Drug-Naïve Patients with Type 2 Diabetes Mellitus and Obesity.” Metabolites Vol.12,11 1092, 2022.
M. Güzey Akansel Et Al., "Effects of the Ketogenic Diet on Microbiota Composition and Short-Chain Fatty Acids in Women with Overweight/Obesity,” Nutrients, Vol.16, No.4374, pp.1-16, 2024.
Wolter, Mathis et al. “Leveraging diet to engineer the gut microbiome.” Nature reviews. Gastroenterology & hepatology Vol.18, Issue.12, pp.885-902, 2021.
Yeşilyurt N., Yilmaz B., Ağagündüz D., Capasso R. Microbiome-based personalized nutrition as a result of the 4.0 technological revolution: A mini literature review // Process Biochemistry. Vol.121, pp.257-262, 2022.
Fitzpatrick, Jessica A et al. “Dietary management of adults with IBD - the emerging role of dietary therapy.” Nature reviews. Gastroenterology & hepatology, Vol.19, Issue.10, pp.652-669, 2022.
Diptarup Mallick, "Analysis of Sex Differential Immunity and its Impacts on Health: A Comprehensive Review," International Journal of Scientific Research in Biological Sciences, Vol.11, Issue.2, pp.56-65, 2024
Kailash Prasad Jaiswal, Arun Kumar Pandey, "An Updates on Medical Mycology Big Data Analytics and Antifungal Therapies," International Journal of Medical Science Research and Practice, Vol.10, Issue.1, pp.1-7, 2023
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors contributing to this journal agree to publish their articles under the Creative Commons Attribution 4.0 International License, allowing third parties to share their work (copy, distribute, transmit) and to adapt it, under the condition that the authors are given credit and that in the event of reuse or distribution, the terms of this license are made clear.
Download Article Template
