Molecular Docking studies against Glioblastoma Proteins
Keywords:
Autodock Vina, Docking program, Autodock 4Abstract
Glioblastoma is a very aggressive tumor that arises from glial cells called astrocytes. It is a malignant brain tumor that unfortunately those affected generally die within a few months, even if they have undergone all the necessary treatments. This short theoretical communication aims to perform several Glioblastoma proteins by the Molecular Docking approach. From these results, Hypericin has shown high binding energies values ( - 10.22 kcal/mol) in human ALDH1A3 ( Aldehyde Dehydrogenase), while Curcumin, Polydatin, and drug Bemcentinib ( -10.32 kcal/mol, -9.69 kcal/mol and -13.28 kcal/mol respectively) with human LSD1 ( Lysine-specific demethylase 1).
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