Factors Affecting Medication Adherence among Patients on Concomitant Tuberculosis and Antiretroviral Therapy in Kogi State Nigeria

Authors

  • Blessing Onyinye Ukoha-Kalu Dept. of Clinical Pharmacy and Pharmacy Management, Faculty of Pharmaceutical Sciences, University of Nigeria Nsukka, Nigeria
  • Florence Eichie Dept. of Pharmaceutics, Faculty of Pharmacy, University of Benin Benin City, Edo State Nigeria
  • Maxwell Ogochukwu Adibe Dept. of Clinical Pharmacy and Pharmacy Management, Faculty of Pharmaceutical Sciences, University of Nigeria Nsukka, Nigeria
  • Chinwe Victoria Ukwe Dept. of Clinical Pharmacy and Pharmacy Management, Faculty of Pharmaceutical Sciences, University of Nigeria Nsukka, Nigeria

Keywords:

Adherence, HIV, AIDs, antiretrovirals

Abstract

Non-adherence to antiretroviral (ARV) medications as well as drugs used to treat tuberculosis (TB) can lead to manifestations of drug-resistant strains of mycobacterium tuberculosis. This study aimed at assessing the level of medication adherence and its determinants among patients living with HIV/AIDS and TB co-morbidity. A well structured questionnaire for the study of ART and anti TB medication adherence and its determinants was designed and the validity of the questionnaires was assessed through in-depth discussion with experienced consultants working in the ARD/TB clinic of the Federal Medical Center, Lokoja. Primary outcome measure was medication adherence, while secondary outcome measures were health literacy of patients and patient relation with their healthcare providers. Data was extracted from completed questionnaires, coded and entered into the Microsoft excel sheet for statistical analysis using SPSS 16.0 A total of 450 patients that participated in the study were on antiretroviral and only 60 (13.3%) of them were co-infected with both HIV and tuberculosis and are on both ARV and TB medications. Majority of the respondents were male (63.3%) and are above 45 years of age. About 23 of the patients were said to be single, 20 patients were married, and 8 of them were divorced/separated while 17 of them were widowed. About 81.7% of the respondents have one form of education or the other. Less than half of the respondents have a source of income. 23 persons (38.3%) reported never to have missed their ARV’s while only 18 persons (30%) reported never to have missed their tuberculosis medications. About 8 patients (13.3%) for ARV’s and 10 patients (16.7%) for anti-TB reported ‘forgetfulness’ as the reason for missing their medications. Majority of the patients (31.7% for ARV’s and 18.3% for anti-TB) reported that experiencing side effects was the reason for missing their medications. Also most of the patients (11.7% for ARV’s and 20.0% for anti TB) said the reason they missed their medications was because they did not have money to transport themselves to the health facility. 

 

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Published

2019-12-31

How to Cite

[1]
B. O. Ukoha-Kalu, Florence Eichie, M. O. Adibe, and C. V. Ukwe, “Factors Affecting Medication Adherence among Patients on Concomitant Tuberculosis and Antiretroviral Therapy in Kogi State Nigeria”, Int. J. Sci. Res. Biol. Sci., vol. 6, no. 6, pp. 129–134, Dec. 2019.

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Section

Research Article